Marie Curie Research Fellow
School of Medicine
Post Reference: 5431
Salary scale: £34,000 per annum plus mobility allowance
Closing Date: 27 May 2010
Description:
Applications are invited for a Marie Curie Research Fellow in the Reproductive Biology Group, School of Medicine, reference 5431, to work on an FP7 Industry-Academia Partnerships and Pathways (IAPP) project. The aim is to develop and apply techniques to study DNA/protein interactions and histone modifications in human disease samples to identify gene targets and molecular pathways that distinguish the activity of antiestrogens from estrogens in breast and endometrium, The successful candidate will take a lead role in the implementation of techniques including Chromatin Immunoprecipitation (ChIP) and DNA methylation detection to formalin fixed, paraffin-embedded human tissue samples.
The successful candidate will join a team of researchers investigating the impact of aberrant transcription processes in the endometrium on infertility and gynaecological cancer. due to abnormalities through The candidate will contribute to a major aim of the group in developing biomarkers for clinical use.
The successful applicant will be based in the £50 million Institute for Life Sciences (ILS) at Swansea University, where interdisciplinary research will be fostered, particularly within Cancer Research and Reproductive Sciences. The successful applicant will also work with project partners in the Department of Pathology in the adjacent Singleton Hospital, Abertawe Bro Morgannwg University Health Board.
This position is supported by the EU Marie Curie programme, and candidates can be a national of a Member State, Associated country or Third country. Further, the researcher must not be a UK national and must not have resided or carried out his/her main activity (work, studies, etc) in the UK for more than 12 months in the previous 3 years, or if a UK national must have spent at least 3 of the previous 4 years outside of the UK.
Applicants must have a PhD in Cell and Molecular Biology or a related discipline and must have knowledge of Epigenetic regulation of Transcription and experience of ChIP methodology.. The candidate must be skilled at developing and working with innovative techniques. The FP7 grant work will be performed in collaboration with Active Motif SA, Belgium, so the candidate must be able to develop effective working relationships with external collaborators.
The post is available for a fixed term period of up to 24 months.
Informal enquiries may be made to Dr Steve Conlan r.s.conlan@swansea.ac.uk. Further information can be found at http://www.medicine.swan.ac.uk/index.html.
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