PhD studentship, at Center for Systems Biology, University of Iceland
The Center for Systems Biology, University of Iceland , is looking to recruit a highly motivated PhD student in Bioinformatics/Systems Biology. The research at the CSB UoI focuses on 1> human metabolism and 2> industrial biotechnology. The Center is an interdisciplinary center with the Schools of Medicine, Engineering and Natural Sciences participating.
Systems biology is a new and rapidly growing discipline. It is widely believed to have a broad transformative potential on both basic and applied studies in the life sciences. In particular, metabolic network reconstructions are playing a key role as they provide a framework for investigation of the mechanism underlying the genotype-phenotype relationship. Recently, the first fine-grained, sequence dependent model of transcription and translation for Escherichia coli has been published. This network was subsequently integrated with the available metabolic model yielding in the most comprehensive stoichiometric model of a cell, to-date. In this master thesis, a similar reconstruction effort will be performed for metabolic genes present in a eukaryotic metabolic network. This resulting network will be used to predict the necessary proteome to drive metabolism in various conditions. This effort represents to first of its kind and will have great impact in computational systems!
biology and in understanding the genetic basis of the eukaryotic organism.
Job description:
• Computational modeling of transcriptional and translational events in eukaryotic cells.
• Development of computational methods to predict cellular proteome.
• Development of a comprehensive knowledge of cellular process and systems biology methods.
Your qualifications:
• Master-level study in Bioinformatics, Systems Biology, Biochemistry, Biotechnology or Medicine.
• Strong interest in molecular biology and computational modeling.
• Good experience in programming and statistical data analysis.
• Excellent communication skills and team orientated work.
• Excellent knowledge of written and spoken English.
Our Offer:
• Working in a scientifically stimulating, innovative, dynamic, well- equipped, and international surrounding.
• In-depth training in cutting edge technologies used in systems biology.
• Numerous training opportunities in biology, systems biology and bioinformatics.
The position is available immediately. Please send a cover letter, a brief description of research experience and interests, a curriculum vitae and contact information for three references in pdf file format to Ines Thiele, PhD .
All applications will be answered and applicants will be informed about the appointment when a decision has been made. A limited research stipend is available for this position.
Appointments to the Center for Systems Biology do take into account the Equal Rights Project of the University of Iceland.
Subscribe for more updates
Posts
