The Marie Curie Initial Training Network on Muscle Z-disk Protein Complexes: from atomic structure to physiological function (ITN MUZIC) offers
1 PhD Position in the Djinovic Carugo Lab
and a total of 9 ESR (PhD) and 4 ER (Post-doctoral) positions in cellular and structural biology
Application deadline: November 7, 2009
Please use the application form offered on this website (download area)
To apply send application to muzic@univie.ac.at, for more information contactkristina.djinovic@univie.ac.at
All partners of except for Stockholm offer ESR positions, Leeds, Stockholm, Vienna and Hamburg offer also ER positions.
Main Research Field
Cellular and Structural Biology
Job Summary
The Marie Curie Initial Training Network on Muscle Z-disk Protein Complexes: from atomic structure to physiological function (ITN MUZIC), funded by the European Commission is filling 9 Doctoral and 4 Postdoctoral positions at 8 Universities/Research Institutions in 6 European countries (from November 2009 on until all positions are filled).
ITN MUZIC aims are
• To bridge the gap between cellular and structural biology by creating a training program that will incorporate both disciplines in the study of molecular components and the cellular mechanisms of the muscle Z-disk. Within the network, young researchers will be trained in a set new, highly versatile research title: "Cellular Structural Biologist".
• To advance knowledge in the area of muscle Z-disk protein complexes, interactions and functions in healthy and diseased cells by understanding the atomic structure of selected components central to Z-disk integrity, their molecular architecture, the dynamic changes of the Z-disk interactome and signalling pathways regulating its development and remodelling.
The ITN MUZIC research programme is organised in four work packages (WP):
• Atomic structure of filamin, telethonin and alpha–actinin in the Z-disk – WP1
• Z-disk Ultrastructure and Molecular Architecture of Its Complexes – WP2
• Dynamic changes of the Z-disk interactome – WP3
• Signalling pathways regulating Z-disk development and remodelling – WP4
Job Description
The partners of ITN MUZIC are dedicated to producing the next generation of research scholars working in the interdisciplinary field of cellular structural biology. ESR and ER's individual projects will be integrated into one comprehensive research and training network. In order to train Cellular Structural Biologists profile they will be offered an innovative training in a unique combination of scientific methods that span from biophysical characterisation of proteins and their complexes, high resolution (X-ray crystallography) and low resolution structural biology methods (SAXS, EM, cryo-EM tomography, atomic force microscopy) to a variety of cell biology oriented techniques, ranging from FRET and live-cell imaging, cellular and animal models to animal physiology.
The network is strongly based on the exchange and transfers of knowledge between participating institutions and will provide its fellows with network-wide training activities (workshops, summer schools, scientific symposium) and training-in-collaborations (working visits and secondments).
ITN MUZIC partners and their fields of research:
1. Kristina Djinovic Carugo (Coordinator, Univ. Vienna, Austria) – Structural Biology of Z-Disk with focus on the a-actinin interactome (WP1, WP2); to apply send application tomuzic@univie.ac.at, for more information contact kristina.djinovic@univie.ac.at
2. Dieter Fürst (Univ. Bonn, Germany) – Cell Biology of Z-Disk with focus on protein localization, dynamics and interactions in living cells (WP3, WP4); to apply send application tozellbiologie@uni-bonn.de, for more information contact dfuerst@uni-bonn.de@univie.ac.at
3. Stefano Schiaffino and Gerolamo Lanfranchi (Univ. Padova, Italy) – Cell Biology of Z-Disk with focus on signalling pathways involved in mechanical stimuli and on functional genomic analysis of muscle cell silencing (WP4); to apply send application to stefano.schiaffino@unipd.itor gerolamo.lanfranchi@unipd.it, for more information contact stefano.schiaffino@unipd.it orgerolamo.lanfranchi@unipd.it
4. Matthias Wilmanns (EMBL-Hamburg, Germany) – Structural Biology of Z-Disk with focus on the titin interactome(WP1, WP2); to apply send application wilmanns@embl-hamburg.de, for more information contact wilmanns@embl-hamburg.de
5. Jari Ylänne (Univ. Jyväskylä, Finland) – Structural and Cell Biology of Z-Disk with focus on intra-subunit interactions in filamin (WP1, WP2, WP3); to apply send application contactjylanne@bytl.jyu.fi, for more information contact jylanne@bytl.jyu.fi
6. John Trinick (Univ. Leeds, UK) – Structural Biology of Z-Disk with focus on the Z-disk ultrastructure (WP2); to apply send application to j.trinick@leeds.ac.uk, for more information contact j.trinick@leeds.ac.uk
7. Mathias Gautel (King's College London, UK) – Cell Biology of Z-Disk with focus on regulation of Z-disk protein interactions by phosphorylation (WP2, WP3, WP4); to apply send application to mathias.gautel@kcl.ac.uk, for more information contact mathias.gautel@kcl.ac.uk
8. Matthias Rief (Technical University Muenchen, Germany) – Structural Biology of Z-Disk with focus on biomechanical properties of filamin (WP1, WP2); to apply send application tomrief@ph.tum.de, for more information contact mrief@ph.tum.de
9. Evitra AB (Stockholm, Sweden) – Protein production (WP1, WP2); to apply send application to Marina.Sabet@ki.se, for more information contact Marina.Sabet@ki.se orPar.Nordlund@ki.se
Early Stage Researchers
Must be in the first 4 years (full-time equivalent) of research career since gaining a university diploma giving access to doctoral studies.
• The length of individual appointment will be limited to between 3 and 36 months.
• The basic gross living allowance for the Early Stage Researcher Fellowships is up to about 33.800 €/year mobility allowance + travel allowance + career exploratory allowance
Experienced Researchers
• Must either be in possession of a doctoral degree or have at least 4 years of full-time equivalent research experience;
• The research experience may not exceed 5 years at the time of appointment.
• The length of individual appointment will be limited from 3 to 24 months.
• The basic gross living allowance for the Experienced Researcher Fellowships is up to about 52..000 €/year mobility allowance + travel allowance + career exploratory allowance
All candidates must NOT be nationals of the country where they seek employment, or have legally resided or have had their main activity in that country for more than 12 months in the 3 years immediately prior to the starting date.
For more information on the recruitment and allowances please see the Annex III to the Grant Agreement from pages 8 – 11: ftp://ftp.cordis.europa.eu/pub/fp7/docs/fp7-mga-annex3intramulti_en.pdf
For further information on these vacancies please contact individual Partners.
Application deadline: November 7, 2009
Please indicate which institution(s) you would like to be considered for in the application.
The completed application form, official diploma document and the letters of recommendation have to be sent to individual Partners.
Posts
