Uveal melanoma has been chosen as a model to engineer a highly innovative immunological vaccine, which can be readily adapted to other cancers. In order to trigger immunity via antigen presenting cells, the team has identified HLA-DR1 and HLA-DR4 restricted peptides derived from Tyrosinase and p53 as novel immunogenic antigens. Unfortunately, peptides on their own show low immunogenicity. This project will look to assess and optimise immunisation strategies using a novel peptide vaccine delivery system constructed from nanoengineered scaffolds. The results from this study will provide a highly innovative approach to the formulation and delivery of immunotherapeutic cancer vaccines.
Entry requirement
A first class or upper second class UK BSc (Hons) degree (or equivalent) in a Chemistry/Biomolecular Science, preferably with a Masters or MRES degree or equivalent scientific laboratory experience.
Eligibility
Applications can be accepted from UK/EU and also International students. The minimum English language proficiency requirement for candidates who have not undertaken a higher degree at a UK HE institution is IELTS 6.5 or TOEFL 560/iBT 94-95.
Applying
For informal enquiries about the studentship, please contact Dr Gareth Cave.
For an application form, please email sat.research@ntu.ac.uk or telephone: +44 (0)115 848 3269, or alternatively download a copy herewww.ntu.ac.uk/research/research_degrees/studentships/96287.html
Please return the completed application form, with copies of academic and English proficiency (if applicable) certificates, to:
The Research Graduate Studies Office (Science)
Erasmus Darwin Building
Nottingham Trent University
Clifton Lane
Nottingham
NG11 8NS
Funding Notes
Fees (2009/2010)
Full-time PhD registration is for a minimum of three years and a maximum of four years.
Home/EU tuition fees: £3,390 (likely to rise in each subsequent year)
International tuition fees: £10,200 (likely to rise in each subsequent year)
Bench fee (annual): £3,000
If a student has not submitted his/her thesis by the end of Year Three, he/she is required to enrol for a fourth year and pay the Continuation Fee to enable him/her to complete and submit the thesis. The Continuation Fee is currently £300 (increases every year). No Bench fee is payable in Year Four.
Entry requirement
A first class or upper second class UK BSc (Hons) degree (or equivalent) in a Chemistry/Biomolecular Science, preferably with a Masters or MRES degree or equivalent scientific laboratory experience.
Eligibility
Applications can be accepted from UK/EU and also International students. The minimum English language proficiency requirement for candidates who have not undertaken a higher degree at a UK HE institution is IELTS 6.5 or TOEFL 560/iBT 94-95.
Applying
For informal enquiries about the studentship, please contact Dr Gareth Cave.
For an application form, please email sat.research@ntu.ac.uk or telephone: +44 (0)115 848 3269, or alternatively download a copy herewww.ntu.ac.uk/research/research_degrees/studentships/96287.html
Please return the completed application form, with copies of academic and English proficiency (if applicable) certificates, to:
The Research Graduate Studies Office (Science)
Erasmus Darwin Building
Nottingham Trent University
Clifton Lane
Nottingham
NG11 8NS
Funding Notes
Fees (2009/2010)
Full-time PhD registration is for a minimum of three years and a maximum of four years.
Home/EU tuition fees: £3,390 (likely to rise in each subsequent year)
International tuition fees: £10,200 (likely to rise in each subsequent year)
Bench fee (annual): £3,000
If a student has not submitted his/her thesis by the end of Year Three, he/she is required to enrol for a fourth year and pay the Continuation Fee to enable him/her to complete and submit the thesis. The Continuation Fee is currently £300 (increases every year). No Bench fee is payable in Year Four.
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